PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31162673-0 2019 Chalcone Derivative L6H21 Reduces EtOH + LPS-Induced Liver Injury Through Inhibition of NLRP3 Inflammasome Activation. (2E)-3-(2,3-Dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one 20-25 NLR family, pyrin domain containing 3 Mus musculus 88-93 31162673-10 2019 In addition, L6H21 treatment markedly inhibited EtOH + LPS-elevated hepatic protein levels of NLRP3, cleaved caspase-1, cleaved IL-1beta, and caspase-1-associated apoptosis. (2E)-3-(2,3-Dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one 13-18 NLR family, pyrin domain containing 3 Mus musculus 94-99 31162673-11 2019 CONCLUSIONS: Our results demonstrate that L6H21 treatment inhibits EtOH + LPS-induced liver steatosis and injury through suppression of NLRP3 inflammasome activation. (2E)-3-(2,3-Dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one 42-47 NLR family, pyrin domain containing 3 Mus musculus 136-141