PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31136032-0	2019	Hyperglycemia induces NF-kappaB activation and MCP-1 expression via downregulating GLP-1R expression in rat mesangial cells: inhibition by metformin.	Metformin	139-148	glucagon-like peptide 1 receptor	Rattus norvegicus	83-89	
31136032-7	2019	We further proved that metformin restored high glucose-inhibited GLP-1R mRNA expression and decreased high glucose evoked inflammation in HBZY-1 cells.	Metformin	23-32	glucagon-like peptide 1 receptor	Rattus norvegicus	65-71	
31136032-8	2019	On the basis of these findings, we conclude that high glucose lowers GLP-1R expression and leads to inflammatory responses in mesangial cells, which can be reversed by metformin.	Metformin	168-177	glucagon-like peptide 1 receptor	Rattus norvegicus	69-75	
31136032-9	2019	These data support the rationale of combinative therapy of metformin with GLP-1R agonists in DN.	Metformin	59-68	glucagon-like peptide 1 receptor	Rattus norvegicus	74-80