PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31123968-0 2019 Cilostazol add-on therapy for celecoxib synergistically inhibits proinflammatory cytokines by activating IL-10 and SOCS3 in the synovial fibroblasts of patients with rheumatoid arthritis. Celecoxib 30-39 suppressor of cytokine signaling 3 Homo sapiens 115-120 31123968-5 2019 Cilostazol and celecoxib cotreatment similarly showed synergistic increase in SOCS3 mRNA levels. Celecoxib 15-24 suppressor of cytokine signaling 3 Homo sapiens 78-83 31123968-8 2019 Summarizing, cotreatment with cilostazol and celecoxib exhibited a synergistic increase in IL-10 production and SOCS3 expressions, thereby resulted in synergistic decreases in IL-1beta mRNA, IL-6 mRNA expression and TNF-alpha synthesis in association with synergistic decreases in COX-2 and PGE2 protein expression in the RA synovial fibroblasts. Celecoxib 45-54 suppressor of cytokine signaling 3 Homo sapiens 112-117