PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31079497-0	2019	Effects of Srxn1 on growth and Notch signalling of astrocyte induced by hydrogen peroxide.	Hydrogen Peroxide	72-89	sulfiredoxin 1	Homo sapiens	11-16	
31079497-1	2019	OBJECTIVE: To investigate the effect of Sulfiredoxin-1 (Srxn1) on astrocyte injury induced by hydrogen peroxide (H2O2).	Hydrogen Peroxide	94-111	sulfiredoxin 1	Homo sapiens	40-54	
31079497-1	2019	OBJECTIVE: To investigate the effect of Sulfiredoxin-1 (Srxn1) on astrocyte injury induced by hydrogen peroxide (H2O2).	Hydrogen Peroxide	94-111	sulfiredoxin 1	Homo sapiens	56-61	
31079497-1	2019	OBJECTIVE: To investigate the effect of Sulfiredoxin-1 (Srxn1) on astrocyte injury induced by hydrogen peroxide (H2O2).	Hydrogen Peroxide	113-117	sulfiredoxin 1	Homo sapiens	40-54	
31079497-1	2019	OBJECTIVE: To investigate the effect of Sulfiredoxin-1 (Srxn1) on astrocyte injury induced by hydrogen peroxide (H2O2).	Hydrogen Peroxide	113-117	sulfiredoxin 1	Homo sapiens	56-61	
31079497-2	2019	METHODS: Observing the changes of H2O2 on contents of lactate dehydrogenase (LDH), malondialdehyde (MDA), superoxide dismutase (SOD) and apoptosis after transfected Srxn1 siRNA into astrocytes.	Hydrogen Peroxide	34-38	sulfiredoxin 1	Homo sapiens	165-170	
31079497-4	2019	RESULTS: Knockdown of Srxn1 could promote the secretion of LDH and MDA, decrease the activity of SOD and aggravate apoptosis of astrocytes induced by H2O2.	Hydrogen Peroxide	150-154	sulfiredoxin 1	Homo sapiens	22-27	
31079497-5	2019	The results of Western blot, ELISA assay and flow cytometry indicated that activation of the Notch signalling pathway attenuated the effect of Srxn1 on H2O2-induced oxidative damage and apoptosis of astrocytes.	Hydrogen Peroxide	152-156	sulfiredoxin 1	Homo sapiens	143-148	
31079497-6	2019	CONCLUSION: Srxn1 may protect astrocytes from oxidative stress injury induced by H2O2 by activation of Notch signalling pathway.	Hydrogen Peroxide	81-85	sulfiredoxin 1	Homo sapiens	12-17