PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31078568-0	2019	Inhibition of protein nitration prevents cisplatin-induced inactivation of STAT3 and promotes anti-apoptotic signaling in organ of Corti cells.	Cisplatin	41-50	signal transducer and activator of transcription 3	Mus musculus	75-80	
31078568-3	2019	Cisplatin-induced nitration and degradation of LMO4 could destabilize this protein complex, which in turn could compromise the downstream STAT3-mediated cellular defense mechanism.	Cisplatin	0-9	signal transducer and activator of transcription 3	Mus musculus	138-143	
31078568-4	2019	Here, we investigated the link between cisplatin-induced nitrative stress and STAT3-mediated apoptosis by using organ of Corti cell cultures.	Cisplatin	39-48	signal transducer and activator of transcription 3	Mus musculus	78-83	
31078568-6	2019	Immunoblotting and immunostaining indicated that cisplatin treatment decreased the expression levels, phosphorylation, and nuclear localization of STAT3 in UB/OC1 cells.	Cisplatin	49-58	signal transducer and activator of transcription 3	Mus musculus	147-152	
31078568-7	2019	Inhibition of nitration by SRI110 co-treatment prevented cisplatin-induced inactivation of STAT3 and promoted its nuclear localization.	Cisplatin	57-66	signal transducer and activator of transcription 3	Mus musculus	91-96	
31078568-8	2019	SRI110 co-treatment reversed the cisplatin-induced changes in the expression levels of Bcl2l1, Ccnd1, Jak2, Jak3, and Src and significantly attenuated the changes in the expression levels of Cdkn1a, Egfr, Fas, Il6st, Jak1, Stat3, and Tyk2.	Cisplatin	33-42	signal transducer and activator of transcription 3	Mus musculus	223-228	
31078568-9	2019	Collectively, these results suggest that the inhibition of cisplatin-induced nitration prevents the inactivation of STAT3, which in turn enables the transcription of anti-apoptotic genes and thereby helps to mitigate cisplatin-induced toxicity.	Cisplatin	59-68	signal transducer and activator of transcription 3	Mus musculus	116-121	
31078568-9	2019	Collectively, these results suggest that the inhibition of cisplatin-induced nitration prevents the inactivation of STAT3, which in turn enables the transcription of anti-apoptotic genes and thereby helps to mitigate cisplatin-induced toxicity.	Cisplatin	217-226	signal transducer and activator of transcription 3	Mus musculus	116-121