PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31073076-10 2020 In a pre-clinical model of patient-derived TP53 mutant acute lymphoblastic leukemia, APR-246 reduced leukemia burden and strongly synergized with the genotoxic agent doxorubicin leading to superior leukemia-free survival in vivo. Doxorubicin 166-177 tumor protein p53 Homo sapiens 43-47