PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31058500-4	2019	EF-Tu alternates between GTP- and GDP-bound conformations during its functional cycle, representing the "on" and "off" states, respectively.	Guanosine Diphosphate	34-37	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	0-5	
31058500-6	2019	Additionally, molecular dynamics (MD) simulations indicate that enthalpic stabilization of GDP binding compared to GTP binding originates in the backbone hydrogen bonding network of EF-Tu.	Guanosine Diphosphate	91-94	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	182-187	
31058500-7	2019	In contrast, binding of GTP to EF-Tu is entropically driven by the liberation of bound water during the GDP- to GTP-bound transition.	Guanosine Diphosphate	104-107	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	31-36	
31058500-8	2019	GDP binding to the apo conformation of EF-Tu is both enthalpically and entropically favored, a feature unique among translational GTPases.	Guanosine Diphosphate	0-3	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	39-44