PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30957679-0 2019 Cigarette smoke exposure induces ROS-mediated autophagy by regulating sestrin, AMPK, and mTOR level in mice. Reactive Oxygen Species 33-36 mechanistic target of rapamycin kinase Mus musculus 89-93 30957679-5 2019 Exposure to CS increased the production of ROS and induced molecular changes in the autophagy pathway, including an increase in phosphorylated AMPK and ULK1, reduction in phosphorylated mTOR, and increases in SESN2, ATG12, and LC3B levels. Cesium 12-14 unc-51 like kinase 1 Mus musculus 152-156 30957679-5 2019 Exposure to CS increased the production of ROS and induced molecular changes in the autophagy pathway, including an increase in phosphorylated AMPK and ULK1, reduction in phosphorylated mTOR, and increases in SESN2, ATG12, and LC3B levels. Cesium 12-14 mechanistic target of rapamycin kinase Mus musculus 186-190 30957679-5 2019 Exposure to CS increased the production of ROS and induced molecular changes in the autophagy pathway, including an increase in phosphorylated AMPK and ULK1, reduction in phosphorylated mTOR, and increases in SESN2, ATG12, and LC3B levels. Cesium 12-14 sestrin 2 Mus musculus 209-214 30957679-5 2019 Exposure to CS increased the production of ROS and induced molecular changes in the autophagy pathway, including an increase in phosphorylated AMPK and ULK1, reduction in phosphorylated mTOR, and increases in SESN2, ATG12, and LC3B levels. Cesium 12-14 autophagy related 12 Mus musculus 216-221 30957679-5 2019 Exposure to CS increased the production of ROS and induced molecular changes in the autophagy pathway, including an increase in phosphorylated AMPK and ULK1, reduction in phosphorylated mTOR, and increases in SESN2, ATG12, and LC3B levels. Cesium 12-14 microtubule-associated protein 1 light chain 3 beta Mus musculus 227-231 30957679-7 2019 When exposure to CS was stopped, there were decreases in the levels of oxidative stress, AMPK and ULK1 phosphorylation, and autophagy-initiating molecules and increase in mTOR phosphorylation. Cesium 17-19 unc-51 like kinase 1 Mus musculus 98-102 30957679-7 2019 When exposure to CS was stopped, there were decreases in the levels of oxidative stress, AMPK and ULK1 phosphorylation, and autophagy-initiating molecules and increase in mTOR phosphorylation. Cesium 17-19 mechanistic target of rapamycin kinase Mus musculus 171-175 30957679-8 2019 In conclusion, these results suggest the involvement of ROS, SESN2, AMPK, and mTOR in the CS-induced autophagic process in the lung. Cesium 90-92 sestrin 2 Mus musculus 61-66 30957679-8 2019 In conclusion, these results suggest the involvement of ROS, SESN2, AMPK, and mTOR in the CS-induced autophagic process in the lung. Cesium 90-92 mechanistic target of rapamycin kinase Mus musculus 78-82