PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30918945-6 2019 RESULTS: Although butyrate promoted Th1 cell development by promoting IFN-gamma and T-bet expression, it inhibited Th17 cell development by suppressing IL-17, Roralpha, and Rorgammat expression. Butyrates 18-26 interferon gamma Mus musculus 70-79 30918945-6 2019 RESULTS: Although butyrate promoted Th1 cell development by promoting IFN-gamma and T-bet expression, it inhibited Th17 cell development by suppressing IL-17, Roralpha, and Rorgammat expression. Butyrates 18-26 T-box 21 Mus musculus 84-89 30918945-6 2019 RESULTS: Although butyrate promoted Th1 cell development by promoting IFN-gamma and T-bet expression, it inhibited Th17 cell development by suppressing IL-17, Roralpha, and Rorgammat expression. Butyrates 18-26 RAR-related orphan receptor alpha Mus musculus 159-167 30918945-7 2019 Interestingly, butyrate upregulated IL-10 production in T cells both under Th1 and Th17 cell conditions. Butyrates 15-23 interleukin 10 Mus musculus 36-41 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 13-21 PR domain containing 1, with ZNF domain Mus musculus 37-78 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 13-21 PR domain containing 1, with ZNF domain Mus musculus 80-86 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 149-157 PR domain containing 1, with ZNF domain Mus musculus 118-124 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 149-157 interleukin 10 Mus musculus 174-179 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 149-157 PR domain containing 1, with ZNF domain Mus musculus 118-124 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 149-157 PR domain containing 1, with ZNF domain Mus musculus 118-124 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 149-157 interleukin 10 Mus musculus 174-179 30918945-8 2019 Furthermore, butyrate induced T-cell B-lymphocyte-induced maturation protein 1 (Blimp1) expression, and deficiency of Blimp1 in T cells impaired the butyrate upregulation of IL-10 production, indicating that butyrate promotes T-cell IL-10 production at least partially through Blimp1. Butyrates 149-157 PR domain containing 1, with ZNF domain Mus musculus 118-124 30918945-9 2019 Rag1-/- mice transferred with butyrate-treated T cells demonstrated less severe colitis, compared with transfer of untreated T cells, and administration of anti-IL-10R antibody exacerbated colitis development in Rag-/- mice that had received butyrate-treated T cells. Butyrates 30-38 recombination activating 1 Mus musculus 0-4 30918945-9 2019 Rag1-/- mice transferred with butyrate-treated T cells demonstrated less severe colitis, compared with transfer of untreated T cells, and administration of anti-IL-10R antibody exacerbated colitis development in Rag-/- mice that had received butyrate-treated T cells. Butyrates 242-250 interleukin 10 receptor, alpha Mus musculus 161-167 30918945-11 2019 CONCLUSIONS: These data indicate that butyrate controls the capacity of T cells in the induction of colitis by differentially regulating Th1 and Th17 cell differentiation and promoting IL-10 production, providing insights into butyrate as a potential therapeutic for the treatment of inflammatory bowel disease. Butyrates 38-46 interleukin 10 Mus musculus 185-190 30918945-11 2019 CONCLUSIONS: These data indicate that butyrate controls the capacity of T cells in the induction of colitis by differentially regulating Th1 and Th17 cell differentiation and promoting IL-10 production, providing insights into butyrate as a potential therapeutic for the treatment of inflammatory bowel disease. Butyrates 227-235 interleukin 10 Mus musculus 185-190