PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30914801-1 2019 Farnesyl diphosphate synthase (FDPS), a mevalonate pathway enzyme, is highly expressed in several cancers, including prostate cancer (PCa). Mevalonic Acid 40-50 farnesyl diphosphate synthetase Mus musculus 0-29 30914801-1 2019 Farnesyl diphosphate synthase (FDPS), a mevalonate pathway enzyme, is highly expressed in several cancers, including prostate cancer (PCa). Mevalonic Acid 40-50 farnesyl diphosphate synthetase Mus musculus 31-35 30914801-9 2019 Pharmacological targeting of FDPS by zoledronic acid (ZOL), which is already in clinics, exhibit reduced growth and clonogenicity of human and murine PCa cells (P < 0.01) and 3D tumoroids (P < 0.02) by disrupting AKT and ERK signaling through direct interference of small GTPases protein prenylation. Zoledronic Acid 37-52 farnesyl diphosphate synthase Homo sapiens 29-33 30914801-9 2019 Pharmacological targeting of FDPS by zoledronic acid (ZOL), which is already in clinics, exhibit reduced growth and clonogenicity of human and murine PCa cells (P < 0.01) and 3D tumoroids (P < 0.02) by disrupting AKT and ERK signaling through direct interference of small GTPases protein prenylation. Zoledronic Acid 37-52 thymoma viral proto-oncogene 1 Mus musculus 213-216 30914801-9 2019 Pharmacological targeting of FDPS by zoledronic acid (ZOL), which is already in clinics, exhibit reduced growth and clonogenicity of human and murine PCa cells (P < 0.01) and 3D tumoroids (P < 0.02) by disrupting AKT and ERK signaling through direct interference of small GTPases protein prenylation. Zoledronic Acid 37-52 mitogen-activated protein kinase 1 Mus musculus 221-224 30914801-9 2019 Pharmacological targeting of FDPS by zoledronic acid (ZOL), which is already in clinics, exhibit reduced growth and clonogenicity of human and murine PCa cells (P < 0.01) and 3D tumoroids (P < 0.02) by disrupting AKT and ERK signaling through direct interference of small GTPases protein prenylation. Zoledronic Acid 54-57 farnesyl diphosphate synthase Homo sapiens 29-33 30914801-9 2019 Pharmacological targeting of FDPS by zoledronic acid (ZOL), which is already in clinics, exhibit reduced growth and clonogenicity of human and murine PCa cells (P < 0.01) and 3D tumoroids (P < 0.02) by disrupting AKT and ERK signaling through direct interference of small GTPases protein prenylation. Zoledronic Acid 54-57 thymoma viral proto-oncogene 1 Mus musculus 213-216 30914801-9 2019 Pharmacological targeting of FDPS by zoledronic acid (ZOL), which is already in clinics, exhibit reduced growth and clonogenicity of human and murine PCa cells (P < 0.01) and 3D tumoroids (P < 0.02) by disrupting AKT and ERK signaling through direct interference of small GTPases protein prenylation. Zoledronic Acid 54-57 mitogen-activated protein kinase 1 Mus musculus 221-224