PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30903363-4 2019 The major molecular targets of metformin include complex I of the mitochondrial electron transport chain, adenosine monophosphate (AMP)-activated protein kinase (AMPK), and mechanistic target of rapamycin complex 1 (mTORC1), but AMPK-independent effects of metformin have also been described. Metformin 31-40 CREB regulated transcription coactivator 1 Mus musculus 216-222