PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30873870-8 2019 Moreover, after pretreatment with N-acetyl-cysteine, Shikonin increased the production of reactive oxygen species that are involved in regulating ER stress-mediated apoptosis and p38-activated autophagy, as evidenced by the reversion of cell viability and apoptosis and a decrease in p-eIF2alpha, CHOP, p-p38, LC3B-II, and Beclin 1 levels. shikonin 53-61 microtubule associated protein 1 light chain 3 beta Homo sapiens 310-314