PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30816216-2 2019 Dysregulation of mTOR signaling has been implicated in the pathogenesis of certain types of ASD, and inhibition of mTOR by rapamycin has been demonstrated to be an effective therapeutics for impaired social interaction in Tsc1+/-, Tsc2+/-, Pten-/- mice and valproic acid-induced ASD animal models. Sirolimus 123-132 phosphatase and tensin homolog Mus musculus 240-244