PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30811219-3 2019 NGI-1 is a small-molecule inhibitor of oligosaccharyltransferase (OST) complexes STT3A-OST and STT3B-OST, which catalyze cotranslational and post-translational N-glycosylation, respectively. Nitrogen 0-1 dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Homo sapiens 66-69 30811219-3 2019 NGI-1 is a small-molecule inhibitor of oligosaccharyltransferase (OST) complexes STT3A-OST and STT3B-OST, which catalyze cotranslational and post-translational N-glycosylation, respectively. Nitrogen 0-1 dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Homo sapiens 87-90 30811219-3 2019 NGI-1 is a small-molecule inhibitor of oligosaccharyltransferase (OST) complexes STT3A-OST and STT3B-OST, which catalyze cotranslational and post-translational N-glycosylation, respectively. Nitrogen 0-1 dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Homo sapiens 87-90 30811219-6 2019 N-glycosylation of 2 representative envelope proteins (gC and gD) was primarily dependent upon STT3A-OST, but to a large extent replaceable by STT3B-OST. Nitrogen 0-1 dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Homo sapiens 101-104 30811219-6 2019 N-glycosylation of 2 representative envelope proteins (gC and gD) was primarily dependent upon STT3A-OST, but to a large extent replaceable by STT3B-OST. Nitrogen 0-1 dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Homo sapiens 149-152 30811219-8 2019 However, with cells lacking STT3B-OST activity (missing the catalytic subunit STT3B or the oxidoreductase subunits magnesium transporter 1/tumor suppressor candidate 3) and thus solely dependent upon STT3A-OST for N-glycosylation, NGI-1 treatment resulted in HSV-1 having cell type-dependent dysfunction (affecting infectivity with Vero cells much more than with the 293 lines). Nitrogen 214-215 dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Homo sapiens 206-209