PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30774881-4 2019 Through an experimental and computational approach using fluorescence polarization, ITC, docking and molecular dynamics simulations we investigate the binding of these functionalized GAG derivatives to ten representative regulatory proteins including IL-8, IL-10, BMP-2, sclerostin, TIMP-3, CXCL-12, TGF-beta, FGF-1, FGF-2, and AT-III, and we establish structure-activity relationships for GAG recognition. Glycosaminoglycans 183-186 C-X-C motif chemokine ligand 8 Homo sapiens 251-255