PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30685760-0	2019	Growth Hormone Response to Oral Glucose Load: From Normal to Pathological Conditions.	Glucose	32-39	growth hormone 1	Homo sapiens	0-14	
30685760-1	2019	The exact physiological basis of acute growth hormone (GH) suppression by oral glucose is not fully understood.	Glucose	79-86	growth hormone 1	Homo sapiens	39-53	
30685760-1	2019	The exact physiological basis of acute growth hormone (GH) suppression by oral glucose is not fully understood.	Glucose	79-86	growth hormone 1	Homo sapiens	55-57	
30685760-3	2019	Attempts to better understand its underlying mechanisms are compromised by species disparities in the response of GH to glucose load.	Glucose	120-127	growth hormone 1	Homo sapiens	114-116	
30685760-4	2019	While in humans, glucose inhibits GH release, the acute elevation of circulating glucose levels in rats has either no effect on GH secretion or may be stimulatory.	Glucose	17-24	growth hormone 1	Homo sapiens	34-36	
30685760-7	2019	Besides the classical suppressive effects of glucose on GH release, a paradoxical GH increase to oral glucose may be observed in around one third of patients with acromegaly as well as in various other disorders.	Glucose	102-109	growth hormone 1	Homo sapiens	82-84	
d the U-II-induced phosphorylation of the redox-sensitive extracellular signal-regulated kinases.	Lycopene	0-8	urotensin 2	Rattus norvegicus	31-35	
24971153-5	2014	Moreover, lycopene treatment prevented the increase in the phosphorylation of serine-threonine kinase Akt and glycogen synthase kinase-3beta (GSK-3 beta ) caused by U-II without affecting the protein levels of the phosphatase and tensin homolog deleted on chromosome 10 (PTEN).	Lycopene	10-18	urotensin 2	Rattus norvegicus	165-169	
24971153-7	2014	These findings imply that lycopene yields antihypertrophic effects that can prevent the activation of the Akt/GSK-3 beta hypertrophic pathway by modulating PTEN inactivation through U-II treatment.	Lycopene	26-34	urotensin 2	Rattus norvegicus	182-186	
24971153-8	2014	Thus, the data indicate that lycopene prevented U-II-induced cardiomyocyte hypertrophy through a mechanism involving the inhibition of redox signaling.	Lycopene	29-37	urotensin 2	Rattus norvegicus	48-52