PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30668347-0 2019 Ovatodiolide suppresses nasopharyngeal cancer by targeting stem cell-like population, inducing apoptosis, inhibiting EMT and dysregulating JAK/STAT signaling pathway. ovatodiolide 0-12 Janus kinase 3 Gallus gallus 139-142 30668347-6 2019 RESULTS: Ova significantly inhibited the viability of BM1 and BM2 cells, downregulated Bcl-xL and Puma, and upregulated Bax/Bad expression levels. ovatodiolide 9-12 BCL2 like 1 Gallus gallus 87-93 30668347-8 2019 Ova-induced apoptosis correlated with increased Bax/Bcl-xL ratio while NPC motility and colony formation inhibition were associated with reduced expression of p-FAK, p-PXN, F-actin, and Slug proteins and increased E-cadherin. ovatodiolide 0-3 BCL2 like 1 Gallus gallus 52-58 30668347-8 2019 Ova-induced apoptosis correlated with increased Bax/Bcl-xL ratio while NPC motility and colony formation inhibition were associated with reduced expression of p-FAK, p-PXN, F-actin, and Slug proteins and increased E-cadherin. ovatodiolide 0-3 snail family transcriptional repressor 2 Gallus gallus 186-190 30668347-8 2019 Ova-induced apoptosis correlated with increased Bax/Bcl-xL ratio while NPC motility and colony formation inhibition were associated with reduced expression of p-FAK, p-PXN, F-actin, and Slug proteins and increased E-cadherin. ovatodiolide 0-3 cadherin 1 Gallus gallus 214-224 30668347-11 2019 CONCLUSIONS: Our results demonstrated the anticancer efficacy of Ova in NPC and its potential as a putative inhibitor of JAK2 and STAT3, which are essential in tumorigenesis of NPC. ovatodiolide 65-68 Janus kinase 2 Gallus gallus 121-125 30668347-11 2019 CONCLUSIONS: Our results demonstrated the anticancer efficacy of Ova in NPC and its potential as a putative inhibitor of JAK2 and STAT3, which are essential in tumorigenesis of NPC. ovatodiolide 65-68 signal transducer and activator of transcription 3 Gallus gallus 130-135