PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30649892-4 2019 Hyperglycemia markedly upregulated the expression of glycolytic enzymes (glucokinase and 6-phosphofructo-1-kinase, PFK1) 5 h following glucose administration, while at 24 h posttreatment, it increased isocitrate dehydrogenase (IDH) activity, a key enzyme of the tricarboxylic acid cycle, and the expression of lipogenic factors (PGC1beta, Lpin1, and SREBP1). Glucose 135-142 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 227-230