PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30605611-5 2019 We demonstrate that the switching between GTP and GDP binding states, which is governed by guanine nucleotide exchange factors (GEFs), GTPase-activating proteins (GAPs), GDI, and GDI displacement factor (GDF), is a major determinant of Rab1"s ability to effectively cycle between cellular compartments and eventually its subcellular distribution. Guanosine Triphosphate 42-45 RAB1A, member RAS oncogene family Homo sapiens 236-240