PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30593501-6	2019	We observed that Grx1 reduces GSH-containing disulfides (including oxidized trypanothione) in very fast reactions (k > 5 x 105 m-1 s-1).	Disulfides	45-55	glutaredoxin	Homo sapiens	17-21	
30593501-9	2019	This kinetic selectivity in the reduction step of the catalytic cycle suggests that Grx1 uses preferentially a dithiol mechanism, forming a disulfide on the active site during the oxidative half of the catalytic cycle and then being rapidly reduced by T(SH)2 in the reductive half.	Disulfides	140-149	glutaredoxin	Homo sapiens	84-88