PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30394213-10 2019 While in absence of water molecule its binding affinity has decreased (-7.3 Kcal/mol with PDE4B enzyme and -5.17 Kcal/mol with PDE4D enzyme) as well as no H-bond interactions were observed. Water 20-25 phosphodiesterase 5A Homo sapiens 90-109