PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30282801-3 2018 Using co-expression in HEK293T cells and co-immunoprecipitation assays, we observed that SIRT7 deacetylates WDR77 at Lys-3 and Lys-243, which reduced of WDR77"s interaction with PRMT5. Lysine 117-120 sirtuin 7 Homo sapiens 89-94 30282801-3 2018 Using co-expression in HEK293T cells and co-immunoprecipitation assays, we observed that SIRT7 deacetylates WDR77 at Lys-3 and Lys-243, which reduced of WDR77"s interaction with PRMT5. Lysine 127-130 sirtuin 7 Homo sapiens 89-94 30282801-6 2018 In summary, SIRT7 is a major deacetylase for WDR77, and SIRT7-mediated deacetylation of WDR77 at Lys-3 and Lys-243 weakens the WDR77-PRMT5 interaction and activity and thereby suppresses growth of cancer cells. Lysine 97-100 sirtuin 7 Homo sapiens 12-17 30282801-6 2018 In summary, SIRT7 is a major deacetylase for WDR77, and SIRT7-mediated deacetylation of WDR77 at Lys-3 and Lys-243 weakens the WDR77-PRMT5 interaction and activity and thereby suppresses growth of cancer cells. Lysine 97-100 sirtuin 7 Homo sapiens 56-61 30282801-6 2018 In summary, SIRT7 is a major deacetylase for WDR77, and SIRT7-mediated deacetylation of WDR77 at Lys-3 and Lys-243 weakens the WDR77-PRMT5 interaction and activity and thereby suppresses growth of cancer cells. Lysine 107-110 sirtuin 7 Homo sapiens 12-17 30282801-6 2018 In summary, SIRT7 is a major deacetylase for WDR77, and SIRT7-mediated deacetylation of WDR77 at Lys-3 and Lys-243 weakens the WDR77-PRMT5 interaction and activity and thereby suppresses growth of cancer cells. Lysine 107-110 sirtuin 7 Homo sapiens 56-61