PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30249603-4	2018	It subsequently delineates how beta2 adrenergic receptor (beta2 AR) signaling via adenylyl cyclase and the cAMP-dependent protein kinase PKA is organized within nanodomains.	Cyclic AMP	107-111	adrenoceptor beta 2	Homo sapiens	58-66	
30249603-5	2018	Here, we discuss targeting of beta2 AR, adenylyl cyclase, and PKA to defined signaling complexes at postsynaptic sites, i.e., AMPARs and the L-type Ca2+ channel Cav1.2, and other subcellular surface localizations, the role of A kinase anchor proteins, the physiological relevance of the spatial restriction of corresponding signaling, and their interplay with signal transduction by the Ca2+- and calmodulin-dependent kinase CaMKII How localized and specific signaling by cAMP occurs is a central cellular question.	Cyclic AMP	472-476	adrenoceptor beta 2	Homo sapiens	30-38