PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30240097-2 2018 It has been hypothesized that upregulation of nuclear FoxO transcription factors and p53 mediate isotretinoin-induced sebocyte apoptosis in vivo. Isotretinoin 97-109 tumor protein p53 Homo sapiens 85-88