PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30240097-0 2018 Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris. Isotretinoin 15-27 forkhead box O1 Homo sapiens 70-75 30240097-3 2018 It is the aim of our study to analyse the distribution of the pro-apoptotic transcription factors FoxO1 and FoxO3 in the nuclear and cytoplasmic compartments of human sebocytes in vivo before and during isotretinoin treatment of acne patients. Isotretinoin 203-215 forkhead box O1 Homo sapiens 98-103 30240097-5 2018 Our in vivo study demonstrates a significant increase in the nucleo-cytoplasmic ratio of non-phosphorylated FoxO1 and FoxO3 during isotretinoin treatment of acne patients. Isotretinoin 131-143 forkhead box O1 Homo sapiens 108-113 30240097-6 2018 Translational and presented experimental evidence indicates that upregulation of nuclear FoxO1 and FoxO3 proteins is involved in isotretinoin-induced pro-apoptotic signalling in sebocytes confirming the scientific hypothesis of isotretinoin-mediated upregulation of FoxO expression. Isotretinoin 129-141 forkhead box O1 Homo sapiens 89-94 30240097-6 2018 Translational and presented experimental evidence indicates that upregulation of nuclear FoxO1 and FoxO3 proteins is involved in isotretinoin-induced pro-apoptotic signalling in sebocytes confirming the scientific hypothesis of isotretinoin-mediated upregulation of FoxO expression. Isotretinoin 228-240 forkhead box O1 Homo sapiens 89-94