PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30031131-2 2018 Among the pleiotropic effects of TNF-alpha within the cell, its binding to TNFR1 receptor has been shown to activate sphingomyelinases leading to the production of ceramides. Ceramides 164-173 tumor necrosis factor Homo sapiens 33-42