PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29997173-6 2018 Thus, soluble CD52 exerts a concerted immunosuppressive effect by first sequestering HMGB1 to nullify its proinflammatory Box B, followed by binding to the inhibitory Siglec-10 receptor, triggering recruitment of SHP1 to the intracellular immunoreceptor tyrosine-based inhibitory motif of Siglec-10 and its interaction with the TCR. Tyrosine 254-262 nuclear receptor subfamily 0 group B member 2 Homo sapiens 213-217