PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29961768-1 2019 PURPOSE: Germline variants in double-strand DNA damage repair (dsDDR) genes (e.g., BRCA1/2) predispose to pancreatic adenocarcinoma (PDAC) and may predict sensitivity to platinum-based chemotherapy and poly(ADP) ribose polymerase (PARP) inhibitors. Platinum 170-178 poly(ADP-ribose) polymerase 1 Homo sapiens 202-229 29961768-1 2019 PURPOSE: Germline variants in double-strand DNA damage repair (dsDDR) genes (e.g., BRCA1/2) predispose to pancreatic adenocarcinoma (PDAC) and may predict sensitivity to platinum-based chemotherapy and poly(ADP) ribose polymerase (PARP) inhibitors. Platinum 170-178 poly(ADP-ribose) polymerase 1 Homo sapiens 231-235