PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29943110-0	2018	Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45beta-dependent manner.	Acetaminophen	45-58	mitogen-activated protein kinase 8	Mus musculus	84-87	
29943110-4	2018	The aim of the present study was to investigate the role of SHP in APAP-evoked hepatotoxicity.	Acetaminophen	67-71	nuclear receptor subfamily 0, group B, member 2	Mus musculus	60-63	
29943110-5	2018	We used lethal (750 mg/kg) or sublethal (300 mg/kg) doses of APAP-treated wild-type (WT), Shp knockout (Shp-/-), hepatocyte-specific Shp knockout (Shphep-/-), and Shp and Gadd45beta double knockout (Shp-/-Gadd45beta-/-) mice for in vivo studies.	Acetaminophen	61-65	nuclear receptor subfamily 0, group B, member 2	Mus musculus	90-93	
29943110-5	2018	We used lethal (750 mg/kg) or sublethal (300 mg/kg) doses of APAP-treated wild-type (WT), Shp knockout (Shp-/-), hepatocyte-specific Shp knockout (Shphep-/-), and Shp and Gadd45beta double knockout (Shp-/-Gadd45beta-/-) mice for in vivo studies.	Acetaminophen	61-65	nuclear receptor subfamily 0, group B, member 2	Mus musculus	104-107	
29943110-5	2018	We used lethal (750 mg/kg) or sublethal (300 mg/kg) doses of APAP-treated wild-type (WT), Shp knockout (Shp-/-), hepatocyte-specific Shp knockout (Shphep-/-), and Shp and Gadd45beta double knockout (Shp-/-Gadd45beta-/-) mice for in vivo studies.	Acetaminophen	61-65	nuclear receptor subfamily 0, group B, member 2	Mus musculus	104-107	
29943110-5	2018	We used lethal (750 mg/kg) or sublethal (300 mg/kg) doses of APAP-treated wild-type (WT), Shp knockout (Shp-/-), hepatocyte-specific Shp knockout (Shphep-/-), and Shp and Gadd45beta double knockout (Shp-/-Gadd45beta-/-) mice for in vivo studies.	Acetaminophen	61-65	nuclear receptor subfamily 0, group B, member 2	Mus musculus	104-107	
29943110-5	2018	We used lethal (750 mg/kg) or sublethal (300 mg/kg) doses of APAP-treated wild-type (WT), Shp knockout (Shp-/-), hepatocyte-specific Shp knockout (Shphep-/-), and Shp and Gadd45beta double knockout (Shp-/-Gadd45beta-/-) mice for in vivo studies.	Acetaminophen	61-65	nuclear receptor subfamily 0, group B, member 2	Mus musculus	104-107	
29943110-11	2018	In Shp-/- mice, APAP-evoked GADD45beta induction was significantly enhanced.	Acetaminophen	16-20	nuclear receptor subfamily 0, group B, member 2	Mus musculus	3-6	
29943110-11	2018	In Shp-/- mice, APAP-evoked GADD45beta induction was significantly enhanced.	Acetaminophen	16-20	growth arrest and DNA-damage-inducible 45 beta	Mus musculus	28-38	
29943110-13	2018	The current study is the first to demonstrate that hepatocyte-specific SHP deficiency protects against APAP overdose-evoked hepatotoxicity in a JNK signaling regulation and GADD45beta dependent manner.	Acetaminophen	103-107	mitogen-activated protein kinase 8	Mus musculus	144-147	
29943110-13	2018	The current study is the first to demonstrate that hepatocyte-specific SHP deficiency protects against APAP overdose-evoked hepatotoxicity in a JNK signaling regulation and GADD45beta dependent manner.	Acetaminophen	103-107	growth arrest and DNA-damage-inducible 45 beta	Mus musculus	173-183