PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29805687-0 2018 Suppression of GRP78 sensitizes human colorectal cancer cells to oxaliplatin by downregulation of CD24. Oxaliplatin 65-76 heat shock protein family A (Hsp70) member 5 Homo sapiens 15-20 29805687-0 2018 Suppression of GRP78 sensitizes human colorectal cancer cells to oxaliplatin by downregulation of CD24. Oxaliplatin 65-76 CD24 molecule Homo sapiens 98-102 29805687-4 2018 In the present study, oxaliplatin (L-OHP) was demonstrated to decrease the expression of CD24 in HT29 cells. Oxaliplatin 22-33 CD24 molecule Homo sapiens 89-93 29805687-4 2018 In the present study, oxaliplatin (L-OHP) was demonstrated to decrease the expression of CD24 in HT29 cells. Oxaliplatin 35-40 CD24 molecule Homo sapiens 89-93 29805687-5 2018 Knockdown of CD24 using small interfering RNA resulted in sensitization of HT29 cells to L-OHP. Oxaliplatin 89-94 CD24 molecule Homo sapiens 13-17 29805687-6 2018 By contrast, overexpression of CD24 rendered SW480 cells resistant to L-OHP, which indicated that CD24 antagonized L-OHP-induced cytotoxicity. Oxaliplatin 70-75 CD24 molecule Homo sapiens 31-35 29805687-6 2018 By contrast, overexpression of CD24 rendered SW480 cells resistant to L-OHP, which indicated that CD24 antagonized L-OHP-induced cytotoxicity. Oxaliplatin 70-75 CD24 molecule Homo sapiens 98-102 29805687-6 2018 By contrast, overexpression of CD24 rendered SW480 cells resistant to L-OHP, which indicated that CD24 antagonized L-OHP-induced cytotoxicity. Oxaliplatin 115-120 CD24 molecule Homo sapiens 31-35 29805687-6 2018 By contrast, overexpression of CD24 rendered SW480 cells resistant to L-OHP, which indicated that CD24 antagonized L-OHP-induced cytotoxicity. Oxaliplatin 115-120 CD24 molecule Homo sapiens 98-102 29805687-8 2018 L-OHP suppresses the expression of GRP78 and CD24, in part come from the inhibition of interaction between the two. Oxaliplatin 0-5 heat shock protein family A (Hsp70) member 5 Homo sapiens 35-40 29805687-8 2018 L-OHP suppresses the expression of GRP78 and CD24, in part come from the inhibition of interaction between the two. Oxaliplatin 0-5 CD24 molecule Homo sapiens 45-49 29805687-9 2018 Suppression of GRP78 caused downregulation of CD24 expression and enhanced L-OHP-induced CD24 inhibition. Oxaliplatin 75-80 heat shock protein family A (Hsp70) member 5 Homo sapiens 15-20 29805687-9 2018 Suppression of GRP78 caused downregulation of CD24 expression and enhanced L-OHP-induced CD24 inhibition. Oxaliplatin 75-80 CD24 molecule Homo sapiens 89-93 29805687-10 2018 Furthermore, down-regulation of GPR78 with a pharmacological inhibitor sensitized the CRC cells to L-OHP. Oxaliplatin 99-104 G protein-coupled receptor 78 Homo sapiens 32-37 29805687-11 2018 Collectively, the present results indicate that CD24 antagonizes L-OHP-induced cytotoxicity and that GRP78 is involved in this process. Oxaliplatin 65-70 CD24 molecule Homo sapiens 48-52 29805687-13 2018 Use of a combination of compounds which suppress GRP78 may help to improve the effectiveness of L-OHP in the treatment of CRC. Oxaliplatin 96-101 heat shock protein family A (Hsp70) member 5 Homo sapiens 49-54