PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29684854-0	2018	The role of Her2-Nrf2 axis in induction of oxaliplatin resistance in colon cancer cells.	Oxaliplatin	43-54	erb-b2 receptor tyrosine kinase 2	Homo sapiens	12-16	
29684854-3	2018	The aim of this study was to investigate the possible cross talk between Nrf2 and Her2 mediated signaling pathways in development of oxaliplatin resistance in colon cancer cells.	Oxaliplatin	133-144	erb-b2 receptor tyrosine kinase 2	Homo sapiens	82-86	
29684854-4	2018	We first generated oxaliplatin-resistant LS174T and SW480 colon cancer cells with different Her2 expression levels by employing IC50 concentrations followed by a resting period.	Oxaliplatin	19-30	erb-b2 receptor tyrosine kinase 2	Homo sapiens	92-96	
29684854-10	2018	Inhibition of either Nrf2 or Her2 alone and in combination caused a significant increase in oxaliplatin-induced cytotoxicity and apoptosis with maximum effects in SW480/Res cells with low Her2 and Nrf2 expression levels.	Oxaliplatin	92-103	erb-b2 receptor tyrosine kinase 2	Homo sapiens	29-33	
29684854-10	2018	Inhibition of either Nrf2 or Her2 alone and in combination caused a significant increase in oxaliplatin-induced cytotoxicity and apoptosis with maximum effects in SW480/Res cells with low Her2 and Nrf2 expression levels.	Oxaliplatin	92-103	erb-b2 receptor tyrosine kinase 2	Homo sapiens	188-192	
29684854-11	2018	Altogether, our results suggest that inhibition of Nrf2 signaling in colon cancer patients with Her2 overexpression can be considered as an important strategy to overcome oxaliplatin resistance.	Oxaliplatin	171-182	erb-b2 receptor tyrosine kinase 2	Homo sapiens	96-100