PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29597170-3 2018 C (5)-substitution of the benzimidazole ring of BRP-7 by carboxylic acid and its bioisosteres provided compounds, exemplified by 57 that potently suppress LT formation (IC50 = 0.05 muM) by targeting FLAP along with inhibition of mPGES-1 (IC50 = 0.42 muM). benzimidazole 26-39 prostaglandin E synthase Mus musculus 229-236