PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29576706-0	2018	Rhynchophylline Downregulates Phosphorylated cAMP Response Element Binding Protein, Nuclear Receptor-related-1, and Brain-derived Neurotrophic Factor Expression in the Hippocampus of Ketamine-induced Conditioned Place Preference Rats.	Ketamine	183-191	brain-derived neurotrophic factor	Rattus norvegicus	116-149	
29576706-4	2018	Objective: To investigate the effects of Rhy on the behavior and the levels of phosphorylated CREB (p-CREB), Nurr1, and BDNF in the hippocampus of ketamine-induced conditioned place preference (CPP) rats.	Ketamine	147-155	brain-derived neurotrophic factor	Rattus norvegicus	120-124	
29576706-8	2018	At the same time, expression of p-CREB, Nurr1, and BDNF, which was significantly increased by ketamine, was restored in the Rhy -treated group.	Ketamine	94-102	brain-derived neurotrophic factor	Rattus norvegicus	51-55	
29576706-10	2018	SUMMARY: P-CREB, Nurr1 and BDNF play an important role in the formation of ketamine-induced place preference in ratsRhynchophylline reversed the expression of p-CREB, Nurr1 and BDNF which was activated by ketamine in the hippocampusRhynchophylline demonstrates the potential effect of mediates ketamine induced rewarding effect.	Ketamine	75-83	brain-derived neurotrophic factor	Rattus norvegicus	27-31	
29576706-10	2018	SUMMARY: P-CREB, Nurr1 and BDNF play an important role in the formation of ketamine-induced place preference in ratsRhynchophylline reversed the expression of p-CREB, Nurr1 and BDNF which was activated by ketamine in the hippocampusRhynchophylline demonstrates the potential effect of mediates ketamine induced rewarding effect.	Ketamine	75-83	brain-derived neurotrophic factor	Rattus norvegicus	177-181	
29576706-10	2018	SUMMARY: P-CREB, Nurr1 and BDNF play an important role in the formation of ketamine-induced place preference in ratsRhynchophylline reversed the expression of p-CREB, Nurr1 and BDNF which was activated by ketamine in the hippocampusRhynchophylline demonstrates the potential effect of mediates ketamine induced rewarding effect.	Ketamine	205-213	brain-derived neurotrophic factor	Rattus norvegicus	177-181	
29576706-10	2018	SUMMARY: P-CREB, Nurr1 and BDNF play an important role in the formation of ketamine-induced place preference in ratsRhynchophylline reversed the expression of p-CREB, Nurr1 and BDNF which was activated by ketamine in the hippocampusRhynchophylline demonstrates the potential effect of mediates ketamine induced rewarding effect.	Ketamine	205-213	brain-derived neurotrophic factor	Rattus norvegicus	177-181