PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29525432-0	2018	Marliolide inhibits skin carcinogenesis by activating NRF2/ARE to induce heme oxygenase-1.	marliolide	0-10	heme oxygenase 1	Homo sapiens	73-89	
29525432-3	2018	In the present study, we identified marliolide as a novel inducer of HO-1 in human normal keratinocyte HaCaT cells.	marliolide	36-46	heme oxygenase 1	Homo sapiens	69-73	
29525432-4	2018	Mechanism-based studies demonstrated that the induction of HO-1 by marliolide occurred through activation of NRF2/ARE via direct binding of marliolide to KEAP1.	marliolide	67-77	heme oxygenase 1	Homo sapiens	59-63	
29525432-4	2018	Mechanism-based studies demonstrated that the induction of HO-1 by marliolide occurred through activation of NRF2/ARE via direct binding of marliolide to KEAP1.	marliolide	140-150	heme oxygenase 1	Homo sapiens	59-63	
29525432-5	2018	Structure-activity relationship revealed chemical moieties of marliolide critical for induction of HO-1, which renders a support for Michael reaction as a potential mechanism of action.	marliolide	62-72	heme oxygenase 1	Homo sapiens	99-103