PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29520229-0	2018	Tacrolimus Reverses UVB Irradiation-Induced Epidermal Langerhans Cell Reduction by Inhibiting TNF-alpha Secretion in Keratinocytes via Regulation of NF-kappaB/p65.	Tacrolimus	0-10	tumor necrosis factor	Homo sapiens	94-103	
29520229-11	2018	Tacrolimus significantly inhibited UVB irradiation-induced tumor necrosis factor-alpha (TNF-alpha) and nuclear factor kappa B (NF-kappaB)/p65 mRNA and protein expression in HaCaT cells.	Tacrolimus	0-10	tumor necrosis factor	Homo sapiens	59-86	
29520229-11	2018	Tacrolimus significantly inhibited UVB irradiation-induced tumor necrosis factor-alpha (TNF-alpha) and nuclear factor kappa B (NF-kappaB)/p65 mRNA and protein expression in HaCaT cells.	Tacrolimus	0-10	tumor necrosis factor	Homo sapiens	88-97	
29520229-12	2018	Tacrolimus also significantly inhibited high-dose UVB irradiation-induced TNF-alpha expression in cultured tissues.	Tacrolimus	0-10	tumor necrosis factor	Homo sapiens	74-83	
29520229-14	2018	Conclusion: Topical tacrolimus 0.03% could reverse UVB irradiation-induced epidermal LC reduction by inhibiting TNF-alpha secretion in keratinocytes via regulation of NF-kappaB/p65.	Tacrolimus	20-30	tumor necrosis factor	Homo sapiens	112-121