PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29448836-6 2018 Newborn UGT1 KO mice treated with AAV had serum total bilirubin levels that were 5.7 times higher than the levels seen in heterozygous and wild-type mice, likely due to dilution of vector genome copies (GC) in the liver resulting from a proliferation of hepatocytes during growth of the animal. Bilirubin 54-63 UDP glucuronosyltransferase 1 family, polypeptide A2 Mus musculus 8-12 29448836-7 2018 The elevation in serum total bilirubin levels in adult UGT1 KO mice depended on the AAV8 vector dose. Bilirubin 29-38 UDP glucuronosyltransferase 1 family, polypeptide A2 Mus musculus 55-59 29448836-11 2018 Therefore, a low-level and likely transient decrease in serum total bilirubin during the first days of life is necessary for rescuing the lethal phenotype present in the neonatal UGT1 KO mouse. Bilirubin 68-77 UDP glucuronosyltransferase 1 family, polypeptide A2 Mus musculus 179-183