PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29273565-0	2018	Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy.	propiverine	108-119	D-amino-acid oxidase	Rattus norvegicus	18-38	
29273565-1	2018	Propiverine, a frequently-prescribed pharmaceutical for the treatment of symptoms associated with overactive bladder syndrome, provoked massive intranuclear and cytosolic protein inclusions in rat proximal tubule epithelium, primarily consisting of the peroxisomal targeting signal 1 (PTS1) containing protein d-amino acid oxidase (DAAO).	propiverine	0-11	D-amino-acid oxidase	Rattus norvegicus	310-330	
29273565-1	2018	Propiverine, a frequently-prescribed pharmaceutical for the treatment of symptoms associated with overactive bladder syndrome, provoked massive intranuclear and cytosolic protein inclusions in rat proximal tubule epithelium, primarily consisting of the peroxisomal targeting signal 1 (PTS1) containing protein d-amino acid oxidase (DAAO).	propiverine	0-11	D-amino-acid oxidase	Rattus norvegicus	332-336	
29273565-4	2018	Corroboration of the role of DAAO- and/or propiverine-specific interaction partners in the drug-induced DAAO accumulation was sought via specific immunofluorescence staining of rat kidney sections from control and propiverine-treated rats.	propiverine	42-53	D-amino-acid oxidase	Rattus norvegicus	104-108	
29273565-4	2018	Corroboration of the role of DAAO- and/or propiverine-specific interaction partners in the drug-induced DAAO accumulation was sought via specific immunofluorescence staining of rat kidney sections from control and propiverine-treated rats.	propiverine	214-225	D-amino-acid oxidase	Rattus norvegicus	29-33	
29273565-4	2018	Corroboration of the role of DAAO- and/or propiverine-specific interaction partners in the drug-induced DAAO accumulation was sought via specific immunofluorescence staining of rat kidney sections from control and propiverine-treated rats.	propiverine	214-225	D-amino-acid oxidase	Rattus norvegicus	104-108	
29273565-5	2018	Above analyses demonstrated the interaction of propiverine with several protein classes, foremost peroxisomal proteins (DAAO, MFE2, HAOX2) and proteins of the protein quality control system, i.e. chaperones (HSP70 and DnaJ co-chaperones), proteases and proteasomal proteins (regulatory subunits of the 26S proteasome; Rpn1/2).	propiverine	47-58	D-amino-acid oxidase	Rattus norvegicus	120-124	
29273565-5	2018	Above analyses demonstrated the interaction of propiverine with several protein classes, foremost peroxisomal proteins (DAAO, MFE2, HAOX2) and proteins of the protein quality control system, i.e. chaperones (HSP70 and DnaJ co-chaperones), proteases and proteasomal proteins (regulatory subunits of the 26S proteasome; Rpn1/2).	propiverine	47-58	hydroxysteroid (17-beta) dehydrogenase 4	Rattus norvegicus	126-130	
29273565-5	2018	Above analyses demonstrated the interaction of propiverine with several protein classes, foremost peroxisomal proteins (DAAO, MFE2, HAOX2) and proteins of the protein quality control system, i.e. chaperones (HSP70 and DnaJ co-chaperones), proteases and proteasomal proteins (regulatory subunits of the 26S proteasome; Rpn1/2).	propiverine	47-58	hydroxyacid oxidase 2	Rattus norvegicus	132-137	
29273565-5	2018	Above analyses demonstrated the interaction of propiverine with several protein classes, foremost peroxisomal proteins (DAAO, MFE2, HAOX2) and proteins of the protein quality control system, i.e. chaperones (HSP70 and DnaJ co-chaperones), proteases and proteasomal proteins (regulatory subunits of the 26S proteasome; Rpn1/2).	propiverine	47-58	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	208-213	
29273565-5	2018	Above analyses demonstrated the interaction of propiverine with several protein classes, foremost peroxisomal proteins (DAAO, MFE2, HAOX2) and proteins of the protein quality control system, i.e. chaperones (HSP70 and DnaJ co-chaperones), proteases and proteasomal proteins (regulatory subunits of the 26S proteasome; Rpn1/2).	propiverine	47-58	ribophorin I	Rattus norvegicus	318-324	
29273565-6	2018	The immunofluorescence analysis revealed mislocalization of many PTS1-proteins (DAAO, CAT, MFE2, ACOX1, EHHADH) in rat renal sections, strongly suggesting that propiverine primarily binds to PTS1 proteins resulting in the formation of PTS1 but not PTS2 or peroxisomal membrane protein (PMP) accumulations.	propiverine	160-171	catalase	Rattus norvegicus	86-89	
29273565-6	2018	The immunofluorescence analysis revealed mislocalization of many PTS1-proteins (DAAO, CAT, MFE2, ACOX1, EHHADH) in rat renal sections, strongly suggesting that propiverine primarily binds to PTS1 proteins resulting in the formation of PTS1 but not PTS2 or peroxisomal membrane protein (PMP) accumulations.	propiverine	160-171	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	Rattus norvegicus	104-110	
29273565-9	2018	Overall, the data presented suggested that propiverine interacts exclusively with DAAO or with a selected number of PTS1 proteins.	propiverine	43-54	D-amino-acid oxidase	Rattus norvegicus	82-86