PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29268182-3 2018 Metyrapone blocks cortisol synthesis, removing negative feedback, and increases the release of hypothalamic CRF and pituitary adrenocorticotropic hormone (ACTH). Metyrapone 0-10 proopiomelanocortin Homo sapiens 155-159 29268182-6 2018 Metyrapone resulted in a greater increase in ACTH and greater decreases in cortisol and delta spectral power sleep in PTSD subjects compared to controls, and a greater increase in ACTH in women compared to men. Metyrapone 0-10 proopiomelanocortin Homo sapiens 45-49 29268182-6 2018 Metyrapone resulted in a greater increase in ACTH and greater decreases in cortisol and delta spectral power sleep in PTSD subjects compared to controls, and a greater increase in ACTH in women compared to men. Metyrapone 0-10 proopiomelanocortin Homo sapiens 180-184