PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29112323-3 2018 Here, we used brefeldin A (BFA) that blocks the activity of the cellular Arf guanine nucleotide exchange factors GBF1, BIG1, and BIG2, which play a major role in reshuffling of cellular membranes. Guanine Nucleotides 77-95 ADP ribosylation factor guanine nucleotide exchange factor 1 Homo sapiens 119-123