PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29107806-7 2018 We show that changes in GluA2 and GluA1 membrane expression in hyperammonemia would be due to enhanced NMDA receptors activation which reduces cGMP levels and phosphodiesterase 2 (PDE2) activity, resulting in increased cAMP levels. Cyclic GMP 143-147 glutamate ionotropic receptor AMPA type subunit 1 Rattus norvegicus 34-39