PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29100274-0 2017 Nicotine induces EP4 receptor expression in lung carcinoma cells by acting on AP-2alpha: The intersection between cholinergic and prostanoid signaling. Nicotine 0-8 transcription factor AP-2 alpha Homo sapiens 78-87 29100274-3 2017 We evaluated whether nicotine increased EP4 receptor expression in lung carcinoma cells by activating on AP-2alpha. Nicotine 21-29 transcription factor AP-2 alpha Homo sapiens 105-114 29100274-6 2017 It indicates that nicotine increases EP4 expression through alpha7 nicotinic acetylcholine receptor-dependent activations of PI3-K, JNK and PKC pathways that leads to reduction of AP-2alpha-DNA binding. Nicotine 18-26 transcription factor AP-2 alpha Homo sapiens 180-189