PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29033541-0 2017 Dexmedetomidine reduces the neuronal apoptosis related to cardiopulmonary bypass by inhibiting activation of the JAK2-STAT3 pathway. Dexmedetomidine 0-15 Janus kinase 2 Rattus norvegicus 113-117 29033541-10 2017 In addition, dexmedetomidine administration inhibits phosphorylation of JAK2 and STAT3 proteins in the hippocampus of rats 2 hours after CPB. Dexmedetomidine 13-28 Janus kinase 2 Rattus norvegicus 72-76 29033541-11 2017 Therefore, we speculate that the JAK2-STAT3 pathway plays an important role in the neuroprotective effects of dexmedetomidine following brain injury induced by CPB. Dexmedetomidine 110-125 Janus kinase 2 Rattus norvegicus 33-37