PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28945481-7 2017 RESULTS: The alleles CYP3A5*3 and CYP3A4*18B were significantly associated with dose-adjusted tacrolimus blood trough concentrations and had a strong time-genotype interaction with tacrolimus pharmacokinetics. Tacrolimus 94-104 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 34-40 28945481-7 2017 RESULTS: The alleles CYP3A5*3 and CYP3A4*18B were significantly associated with dose-adjusted tacrolimus blood trough concentrations and had a strong time-genotype interaction with tacrolimus pharmacokinetics. Tacrolimus 181-191 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 34-40 28945481-10 2017 Thus, genotyping of the CYP3A4 and CYP3A5 genes should be considered with respect to determining tacrolimus dose regimens during the post-transplantation period. Tacrolimus 97-107 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 24-30