PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28871597-10 2017 Mitochondrial pathway of apoptosis was activated in the small intestines of MTX-treated rats as evidenced by intense immunostaining for cyt c, caspases 9 and 3, and PARP-1 and mitochondrial release of cyt c, activation of caspases, and PARP-1 cleavage by Western blot. Methotrexate 76-79 caspase 9 Rattus norvegicus 136-159 28871597-10 2017 Mitochondrial pathway of apoptosis was activated in the small intestines of MTX-treated rats as evidenced by intense immunostaining for cyt c, caspases 9 and 3, and PARP-1 and mitochondrial release of cyt c, activation of caspases, and PARP-1 cleavage by Western blot. Methotrexate 76-79 caspase 9 Rattus norvegicus 143-151 28871597-15 2017 The results of the present study show that the mitochondrial pathway of apoptosis plays a role in MTX-induced small intestinal injury as evidenced by cytochrome c release, activation of caspases 9 and 3, PARP-1 cleavage, and DNA fragmentation. Methotrexate 98-101 caspase 9 Rattus norvegicus 186-202