PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28795389-3	2019	Intracellular calcium ion was imaged to verify PA on mu-opioid receptor (MOR).	patchouli alcohol	47-49	opioid receptor, mu 1	Mus musculus	73-76	
28795389-5	2019	Cellular experiments were carried out to find out COX2 and MOR expression induced by PA.	patchouli alcohol	85-87	opioid receptor, mu 1	Mus musculus	59-62	
28795389-7	2019	PA also up-regulated COX2 mRNA and protein (P<0.05) with a down-regulation of MOR (P<0.05) both in in vivo and in vitro experiments, which devote to the analgesic effect of PA.	patchouli alcohol	0-2	opioid receptor, mu 1	Mus musculus	81-84	
28795389-9	2019	PA showed the characters of enhancing the MOR expression and reducing the intracellular calcium ion similar to opioid effect.	patchouli alcohol	0-2	opioid receptor, mu 1	Mus musculus	42-45	
28795389-10	2019	CONCLUSIONS: Both COX2 and MOR are involved in the mechanism of PA"s anti-nociceptive effect, and the up-regulation of the receptor expression and the inhibition of intracellular calcium are a new perspective to PA"s effect on MOR.	patchouli alcohol	64-66	opioid receptor, mu 1	Mus musculus	27-30	
28795389-10	2019	CONCLUSIONS: Both COX2 and MOR are involved in the mechanism of PA"s anti-nociceptive effect, and the up-regulation of the receptor expression and the inhibition of intracellular calcium are a new perspective to PA"s effect on MOR.	patchouli alcohol	212-214	opioid receptor, mu 1	Mus musculus	227-230