PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28753731-1 2017 A divergent synthesis of optically active quaternary Delta4 - and Delta5 -dehydro prolines is developed based on the first catalytic enantioselective conjugate addition of alpha-substituted isocyano(thio)acetates to vinyl ketones that is general for both alpha-aryl and alpha-alkyl isocyano(thio)acetates. quaternary 42-52 delta like canonical Notch ligand 4 Homo sapiens 59-65