PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28723731-0	2017	Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment.	Methadone	102-111	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	19-25	
28723731-2	2017	The aim of this study was to clarify the impact of the reduced function CYP2B6*6 variant allele together with variants in other candidate genes on a steady-state methadone concentration in a naturalistic setting.	Methadone	162-171	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	72-78	
28723731-6	2017	The estimated mean methadone C/D ratios was 17.8 nmol L mg for homozygous carriers of CYP2B6*6, which was significantly (P < 0.001) higher than noncarriers (9.2 nmol L mg).	Methadone	19-28	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	86-92	
28723731-9	2017	CONCLUSIONS: Patients homozygous for CYP2B6*6 had a >90% higher methadone C/D ratio.	Methadone	67-76	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	37-43	
28723731-10	2017	Genotyping of CYP2B6 may therefore be of value when assessing dose requirements in methadone maintenance treatment.	Methadone	83-92	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	14-20