PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28663050-2 2017 Nuclear factor erythroid 2-related factor 2 (NRF2), a potential target of miR-144, is a central regulator of antioxidant response, and plays an important role in glutathione (GSH) biosynthesis and recycling. Glutathione 162-173 microRNA 144 Homo sapiens 74-81 28663050-2 2017 Nuclear factor erythroid 2-related factor 2 (NRF2), a potential target of miR-144, is a central regulator of antioxidant response, and plays an important role in glutathione (GSH) biosynthesis and recycling. Glutathione 175-178 microRNA 144 Homo sapiens 74-81 28663050-6 2017 GSH and glutathion peroxidase (GPX) activities were detected to reveal the effect of miR-144 on GSH accumulation. Glutathione 96-99 microRNA 144 Homo sapiens 85-92 28663050-8 2017 In oxidative stress conditions, miR-144 increased the intracellular accumulation of ROS, reduced cell viability, reduced the activities of GSH and antioxidant enzymes, GPX1, and decreased the expression of GCLC, GCLM, GR and NRF2. Glutathione 139-142 microRNA 144 Homo sapiens 32-39 28663050-9 2017 In conclusion, miR-144 modulates oxidative stress tolerance by regulating NRF2 expression and GSH generation, which may contribute to the pathogenesis of AD. Glutathione 94-97 microRNA 144 Homo sapiens 15-22