PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28654077-7 2017 As a proof of concept, rotenone, an inhibitor of mitochondrial respiratory complex I, was used to assess the activation of the Nrf2 signaling pathway, a key regulator of the antioxidant-response-element-(ARE)-driven cellular defense mechanism against oxidative stress. Rotenone 23-31 NFE2 like bZIP transcription factor 2 Homo sapiens 127-131