PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28633902-4 2017 However, whether CaSR inhibits the injury of ECs and the activation of platelets by regulating the endogenous cystathionine-gamma-lyase (CSE, a major enzyme that produces H2S)/H2S pathway in hyperhomocysteinemia has not been previously investigated. Hydrogen Sulfide 171-174 cystathionine gamma-lyase Rattus norvegicus 110-135 28633902-4 2017 However, whether CaSR inhibits the injury of ECs and the activation of platelets by regulating the endogenous cystathionine-gamma-lyase (CSE, a major enzyme that produces H2S)/H2S pathway in hyperhomocysteinemia has not been previously investigated. Hydrogen Sulfide 171-174 cystathionine gamma-lyase Rattus norvegicus 137-140 28633902-4 2017 However, whether CaSR inhibits the injury of ECs and the activation of platelets by regulating the endogenous cystathionine-gamma-lyase (CSE, a major enzyme that produces H2S)/H2S pathway in hyperhomocysteinemia has not been previously investigated. Hydrogen Sulfide 176-179 cystathionine gamma-lyase Rattus norvegicus 110-135 28633902-4 2017 However, whether CaSR inhibits the injury of ECs and the activation of platelets by regulating the endogenous cystathionine-gamma-lyase (CSE, a major enzyme that produces H2S)/H2S pathway in hyperhomocysteinemia has not been previously investigated. Hydrogen Sulfide 176-179 cystathionine gamma-lyase Rattus norvegicus 137-140 28633902-12 2017 Our results demonstrate that CaSR regulates the endogenous CSE/H2S pathway to inhibit the activation of platelets which concerts the protection of ECs in hyperhomocysteinemia. Hydrogen Sulfide 63-66 cystathionine gamma-lyase Rattus norvegicus 59-62